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MDAI ( 5,6-methylenedioxy-2-aminoindane) is a drug developed in the 1990s by a team led by David E. Nichols at Purdue University. It acts as a non- neurotoxic and highly selective serotonin releasing agent (SSRA) in vitro and produces entactogen effects in humans.
2-Aminoindane ( 2-AI) is a research chemical with applications in neurologic disorders and psychotherapy that has also been sold as a designer drug. [1] It acts as a selective substrate for NET and DAT. [2] [3]
5-Iodo-2-aminoindane ( 5-IAI) is a drug which acts as a releasing agent of serotonin, norepinephrine, and dopamine. [2] It was developed in the 1990s by a team led by David E. Nichols at Purdue University. [3] 5-IAI fully substitutes for MDMA in rodents and is a putative entactogen in humans. [3] Unlike related aminoindane derivatives like MDAI ...
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MEAI ( 5-methoxy-2-aminoindane or 5-MeO-AI or Chaperon) belongs to the indane family of molecules. Its molecular structure was first mentioned implicitly in a markush structure schema appearing in a patent from 1998. [1] It was later explicitly and pharmacologically described in a peer reviewed paper in 2017 by David Nutt and Ezekiel Golan et ...
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